Research is the key to finding better treatment options for bone marrow transplant patients. Researchers around the world are looking for ways to provide more hope to patients that require a bone marrow transplant:
The Katelyn Bedard Bone Marrow Association sponsors bone marrow transplant related research taking place in Canadian universities and hospitals. We are always looking for new projects to sponsor. If you are a researcher working in a Canadian university or hospital, contactus today to find out how we can contribute to your project at info@givemarrow.net.
Earlier this year, Katelyn Bedard Bone Marrow Association donated $5,000 to the Lisa Porter Research Fund at University of Windsor to help Dr. Lisa Porter and her team research environmental impacts on stem cell development. Dr. Porter and her group are doing cutting edge work and we are proud to support this project. We are confident the results of this work will be of benefit to stem cell transplant patients among others in years to come.
Dr. Porter has provided the following synopsis of her work and how it relates to stem cell transplantation:

"Hematopoietic, or blood forming, stem cells (HSCs) are immature cells capable of maturing into all forms of mature blood cells. HSCs are found in the bone marrow, bloodstream and umbilical cord blood at differing levels. Transplantation of these cells is hampered by the high cell dose required for engraftment. Clinical results in children have clearly shown that the number of stem cells infused during transplantation is correlated closely to the speed of recovery after chemotherapy. Learning how to effectively grow, or expand, HSCs in the laboratory would be an exceptionally valuable tool, enabling us to optimize engraftment using all sources and using limited pools of HSCs. In order to do this we must first identify the factors that regulate how these cells maintain their stem cell properties and what triggers them to become mature blood cells."
"With support from the KBBMA the Porter Lab at the University of Windsor will characterize the role of a central set of proliferative factors in maintaining stem like growth and allowing for effective expansion of HSCs in the laboratory. The factors that will be initially focused on have been previously identified by the Porter group and others as being very important in maintaining stemness in other stem cell populations. In addition to optimizing conditions by which we could expand HSCs in the laboratory, this work may also provide essential basic science information valuable in the diagnosis and treatment of specific forms of leukemia and/or lymphoma"
For additional information see:
We hope to continue supporting this project on an ongoing basis. Thank you to our generous supporters for making this sponsorship possible!
In 2007, the Katelyn Bedard Bone Marrow Association was pleased to make a contribution of five thousand dollars to the research project conducted by Dr. Claude Perreault of the Institute for Research in Immunology and Cancer at the University of Montreal. Dr. Perreault and his team have identified 17 genes that indicate that a candidate bone marrow donor may be "dangerous" in terms of causing graft vs. host disease (GVHD) in the receiving patient following the transplant.
GVHD is a serious, some times fatal complication of bone marrow transplants. According to the National Marrow Donor Program, "In GVHD, the immune cells from the donated marrow or cord blood (the graft) attack the body of the transplant patient (the host). GVHD can affect many different parts of the body. The skin, eyes, stomach and intestines are affected most often. GVHD can range from mild to life-threatening." Dr. Perreault is working to develop a simple test to screen candidate donors prior to being selected to determine if they would put the recipient at a higher risk for GVHD.
Dr. Claude Perreault is the Principal Investigator, Immunobiology Laboratory, Institute for Research in Immunology and Cancer. He is also a Full Professor, Department of Medicine, Université de Montréal and a Hematologist, Maisonneuve-Rosemont Hospital. He is currently the Canada Research Chair in Immunobiology. Additional information about Dr. Perreault and his work can be found here:
The Katelyn Bedard Bone Marrow Association will continue to support Dr. Perreault's research on an ongoing basis. This is only possible thanks to the help of our generous supporters. If you would like to make a donation, follow the link on our ways you can help page.